Nicotine Ditartrate ( (?)-Nicotine Ditartrate )

Catalog No. M19822 CAS No. 65-31-6

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

Nicotine Ditartrate
Note

Research use only not for human use.
Brief Description

(?)-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
Description

(?)-Nicotine is the dominant form of the natural alkaloid nicotine. It acts as an agonist of neuronal nicotinic acetylcholine receptors (nAChRs) and possesses addictive and teratogenic properties. (?)-(S)-Nicotine is significantly more active at binding nAChRs compared to the (+)-(R) antipode thus nicotine is typically synthesized as (?)-(S)-nicotine with only 0.2-1% of the (+)-(R) isomer present.
Synonyms

(?)-Nicotine Ditartrate
Pathway

Endocrinology/Hormones
Target

AChR
Recptor

nAChR
Research Area

Others
Indication

Ulcerative colitis

CAS Number

65-31-6
Formula Weight

462.41
Molecular Formula

C18H26N2O12
Purity

>98% (HPLC)
Solubility

DMSO:198.9 mM
SMILES

O[C@H]([C@@H](O)C(O)=O)C(O)=O.O[C@H]([C@@H](O)C(O)=O)C(O)=O.CN1CCC[C@H]1c1cccnc1
Chemical Name

——